Friday, May 7, 2010

CGHnormaliter: a Bioconductor package for normalization of array CGH data with many CNAs

Summary: CGHnormaliter is a package for normalization of array comparative genomic hybridization (aCGH) data. It uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs). CGHnormaliter is integrated in the Bioconductor environment allowing a smooth link to visualization tools and further data analysis.

Availability and Implementation: The CGHnormaliter package is implemented in R and under GPL 3.0 license available at Bioconductor:


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