Friday, May 7, 2010

CGHnormaliter: a Bioconductor package for normalization of array CGH data with many CNAs

Summary: CGHnormaliter is a package for normalization of array comparative genomic hybridization (aCGH) data. It uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs). CGHnormaliter is integrated in the Bioconductor environment allowing a smooth link to visualization tools and further data analysis.


Availability and Implementation: The CGHnormaliter package is implemented in R and under GPL 3.0 license available at Bioconductor: http://www.bioconductor.org


Contact: heringa@few.vu.nl


(this Post content was reproduced from: http://bioinformatics.oxfordjournals.org/cgi/content/short/26/10/1366?rss=1, Via Bioinformatics - current issue.)