Thursday, May 13, 2010

Tip of the Week: Chromhome, for karyotype level comparative genomics | The OpenHelix Blog

see the OpenHelix tutorial on the dedicated blog
If species A and species B are mapped on species N, then it is possible to deduce some of the chromosomal arrangements of A on B or B on A with respect to the arrangements of N chromosomes. Many of the species in Chromhome have been mapped on human chromosomes using chromosome painting. It is therefore possible to infer homologies between two species each of which have been hybridized with human probes.
So if this type of comparative genomics may be of interest to you, check out Chromhome.
Reference: Nagarajan, S., Rens, W., Stalker, J., Cox, T., & Ferguson-Smith, M. (2008). Chromhome: A rich internet application for accessing comparative chromosome homology maps BMC Bioinformatics, 9 (1) DOI: 10.1186/1471-2105-9-168

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