Saturday, March 26, 2011

A practical comparison of de novo genome assembly

PLoS One. 2011 Mar 14;6(3):e17915.
A practical comparison of de novo genome assembly software tools for next-generation sequencing technologies.
Zhang W, Chen J, Yang Y, Tang Y, Shang J, Shen B.
Center for Systems Biology, Soochow University, Suzhou, Jiangsu, China.
Abstract:
The advent of next-generation sequencing technologies is accompanied with the development of many whole-genome sequence assembly methods and software, especially for de novo fragment assembly. Due to the poor knowledge about the applicability and performance of these software tools, choosing a befitting assembler becomes a tough task. Here, we provide the information of adaptivity for each program, then above all, compare the performance of eight distinct tools ag


(Via PubMed.)