Wednesday, May 25, 2011

BioTechniques - Navigating the human genome

Nice post full of warnings (but no real surprise!).
extract (read the full post)!:
While computational tools can spot single nucleotide polymorphisms (SNPs)—the smallest type of genetic variant—with accuracy, unsuspecting researchers may risk mistaking a false SNP for a true variant. These false SNPs arise from artifacts stemming from sequencing errors and sequence misreads and misalignments. So researchers involved with the 1000 Genomes Project take several measures to ensure their SNP calls represent genuine variation.

By: Vincent Shen 05/24/2011
(Via Biotechniques.)