Saturday, January 26, 2013

Fwd: CRAVAT: Cancer-Related Analysis of VAriants Toolkit

Fwd: please follow footer link

CRAVAT: Cancer-Related Analysis of VAriants Toolkit: "

Summary: Advances in sequencing technology have greatly reduced the costs incurred in collecting raw sequencing data. Academic laboratories and researchers therefore now have access to very large datasets of genomic alterations but limited time and computational resources to analyze their potential biological importance. Here, we provide a web-based application, Cancer-Related Analysis of VAriants Toolkit (CRAVAT), designed with an easy-to-use interface to facilitate the high-throughput assessment and prioritization of genes and missense alterations important for cancer tumorigenesis. CRAVAT provides predictive scores for germline variants, somatic mutations, and relative gene importance, as well as annotations from published literature and databases. Results are emailed to users as MS Excel spreadsheets and/or tab-separated text files.


Supplementary Information: Available at Bioinformatics online


(Via Bioinformatics - Advance Access.)