Friday, January 25, 2013

Fwd: The automatic annotation of bacterial genomes

Fwd: please follow footer link

The automatic annotation of bacterial genomes: "

With the development of ultra-high-throughput technologies, the cost of sequencing bacterial genomes has been vastly reduced. As more genomes are sequenced, less time can be spent manually annotating those genomes, resulting in an increased reliance on automatic annotation pipelines. However, automatic pipelines can produce inaccurate genome annotation and their results often require manual curation. Here, we discuss the automatic and manual annotation of bacterial genomes, identify common problems introduced by the current genome annotation process and suggests potential solutions.

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(Via Briefings in Bioinformatics - recent issues.)